Review
Aug 2026
Drug failure in diabetic kidney disease: translational barriers, target validation and trial de-risking strategies.
Diabetic kidney disease (DKD) remains a difficult therapeutic setting in nephrology, metabolism and clinical pharmacology. Standard care has moved from glucose- and blood-pressure-centred treatment toward disease-modifying therapy built around renin-angiotensin-aldosterone system (RAAS) blockade, sodium-glucose cotrans...
Hong-Tu Hu, Suyue Hou, Wen-Jie Chen et al.
· Biochemical Pharmacology · 0 citations