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Suzanne I. Sandin Lawrence

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Open access Oct 2026

Molecular mechanism of KRAS binding to BRAF and its regulation by the BRAF-specific region

Although the RBD engages KRAS through a conserved mechanism, the BRAF(CRD) adopts a hinge-like displacement away from KRAS, forming fewer contacts and contributing less to binding than CRAF(CRD).

D. Bonsor, Suzanne I. Sandin Lawrence, Timothy H. Tran et al. · 0 citations

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