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Suzanne M. Crumley

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Open access Oct 2026

Cancer cell CD73 loss promotes a dual inflammatory and immunosuppressive microenvironment in endometrial carcinoma.

CD73 is an emerging immunotherapy target that is overexpressed in many tumors and generates an adenosine-rich microenvironment to suppress antitumor immunity. In low-grade endometrial carcinoma (EC), CD73 expression varies, and its impact on tumor immunobiology is unknown. Using two microsatellite-stable, grade 2 endom...

Hannah N. Lee, Xing-Yuan Zhang, Suzanne M. Crumley et al. · 0 citations

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