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Author

Swathi Thoduvayil

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Open access Apr 2026

Association of oxidative stress, inflammation, and ADIPOQ gene expression in young adults at risk of non-alcoholic fatty liver disease and cardiovascular disease

Introduction non-alcoholic fatty liver disease (NAFLD) and cardiovascular diseases (CVD) are increasingly seen in young adults due to obesity, sedentary lifestyle, and poor diet. Oxidative stress and chronic inflammation are key contributors to their development, promoting liver damage, endothelial dysfunction, and ath...

Rachana Raveendran, A. Josephine, V. Sureka et al. · 0 citations
Open access Aug 2026

LEPTIN RECEPTOR GENE EXPRESSION AND ITS ASSOCIATION WITH CARDIOVASCULAR RISK MARKERS IN OBESE SUBJECTS: A CASE–CONTROL STUDY FROM SOUTH INDIA

LEPR gene expression is significantly upregulated in obesity and is positively associated with circulating leptin concentrations, suggesting altered leptin signaling in obese individuals and may serve as a promising molecular biomarker for identifying obesity-associated cardiometabolic risk.

Swathi Thoduvayil, M. Thiruchenduran, D. Divakaran et al. · 0 citations
Open access Jul 2026

Association of APOE gene expression with thyroid dysfunction, inflammation, and nitrosative stress in cardiometabolic syndrome: a case–control study

CMS is characterized by the convergence of thyroid dysregulation, inflammation, oxidative stress, and increased ApoE gene expression, which highlights a coordinated molecular network underlying CMS and support the integration of molecular and inflammatory biomarkers into cardiometabolic risk assessment.

Tha-alnoorein Abdulla, T. Kumar D, J. Inbanathan et al. · 0 citations

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