Neuronal loss in neurodegenerative diseases is mediated by oxidative stress, neuroinflammation, and epigenetic dysregulation, with histone deacetylase 3 (HDAC3) playing a central role in inflammatory signaling and neuronal damage. We...
The developed carbon-based nanoplatform showed significant tumor specificity and inhibition, making it a significant approach for a potential multifunctional treatment strategy for cancer.
Z. Sarkar, Varshini Are, Bhavesha Chanchlani et al.· ACS Applied Nano Materials· 0 citations
Overall, epigenetic modulators present a promising therapeutic approach for neurodegeneration, and continued research integrating various assays like DNA methylation analysis, histone modification analysis, non-coding RNA analysis, neuroinflammation analysis, and functional and behavioral assays in AD models is signifi...
Debojyoti Halder, Denish Prajapati, Tonmoy Banerjee et al.· Methods in Enzymology· 0 citations
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