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Author

Syam Mohan

2 papers indexed here

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Open access Sep 2026

Design, synthesis, and preliminary anticancer evaluation of diphenylpropan-1-one derivatives: in vitro, in vivo and in silico studies

Breast cancer is a leading cause of cancer-associated mortality and morbidity worldwide, and there is a continued need for structurally diverse anticancer agents with improved properties. The present study reports a series of diphenylpropan-1-one (DPP) derivatives (4a–4i), rationally designed around a chalcone framewor...

A. Najmi, M. S. Alam, W. Ahsan et al. · 0 citations
Sep 2026

Hydroxyurea-Loaded Nanostructured Lipid Carriers for Enhanced In Vitro Cytotoxicity and Drug Delivery.

Hydroxyurea (HU) is an established anticancer drug used to treat chronic myelogenous leukemia, but its therapeutic efficacy is limited by rapid clearance, variable bioavailability, and dose-related toxicity. This study aimed to improve HU delivery by developing hydroxyurea-loaded nanostructured lipid carriers (NLCs) us...

O. Madkhali, Mohammad Intakhab Alam, Syam Mohan et al. · 0 citations

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