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Sydney Binns

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Open access Sep 2025

A widespread Actinobacterial G Protein System regulates production of specialized metabolites in Streptomyces coelicolor

Actinobacterial G protein systems (AGPSs), also known as conservons, are regulatory systems that are broadly distributed within Actinomycetota. AGPSs are composed of a minimum of four proteins, including a sensor histidine kinase, a small Ras-like GTPase, a roadblock/MglB protein (likely a GTPase activating protein), a...

Luis M. Cantu Morin, Aditya Vunnum, Sydney Binns et al. · 0 citations
Open access Aug 2026

A widespread actinobacterial G protein system regulates production of specialized metabolites in Streptomyces coelicolor

The Cvn8 AGPS belongs to a group of AGPSs that is found broadly in the genus Streptomyces and in more distantly related orders of Actinomycetota, such as the Pseudonorcardiales and Micromonosporales, which raises the possibility that this group of AGPSs may influence specialized metabolism across a broad range of Actin...

Luis M. Cantu Morin, Aditya Vunnum, Sydney Binns et al. · 0 citations

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