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Author

Sylwia Michlewska

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Open access Aug 2026

Txn-Txnrd1 system supports redox rewiring during polyaneuploid transition and protects giant cancer cells at new redox homeostasis

Polyaneuploid giant cells (PGCC), which occur more frequently in TP53-mutant tumors, are recognized as a driver of tumor recurrence and therapy resistance, but the mechanisms supporting their survival remain largely unknown. Our results indicate that polyaneuploid transition and subsequent PGCC maturation in drug-resis...

Kinga Kołacz-Milewska, K. Gronkowska, Sylwia Michlewska et al. · 0 citations
Open access Aug 2026

Cleavable Carbosilane Dendrimers Modulate the Thermodynamical Properties of DMPC/DPPG Lipid Membrane and Conformation of Human Serum Albumin.

Cationic carbosilane dendrimers are promising nonviral vectors for the delivery of drugs and nucleic acids, however, their interaction with bloodstream molecules is incompletely understood. In this study, we investigated the interactions of a novel family of pH-tunable charge cationic carbosilane dendrimers of three ge...

Paulina Rycharska, Sylwia Michlewska, Adam Buczkowski et al. · 0 citations

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