553. Dual Lipopolysaccharide injection induces prolonged activation of the kynurenine pathway and alters schizophrenia-associated proteins in vivo
Abstract Background Schizophrenia is a severe chronic psychiatric disease that affects approximately 0.3% of the population and imposes a substantial emotional and economic burden on families and society worldwide1,2. It is characterized by positive, negative and cognitive symptoms1. Current treatments address the posi...