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Sep 2026

The Iron Chaperone PCBP2 Controls Systemic Iron Homeostasis by Regulating Iron Flux in Red Pulp Macrophages.

Systemic iron homeostasis critically depends on macrophages for the recycling of iron from senescent erythrocytes. The iron chaperone poly(rC)-binding protein 2 (PCBP2) is considered to direct intracellular iron trafficking. However, its specific role in macrophage-mediated iron redistribution remains unclear. We show...

M. Grander, Lukas Mueller, M. Trebo et al. · 0 citations
Review Open access Aug 2026

Diet in IBD: preventive and therapeutic concepts.

The potential of dietary interventions as a therapy for IBDs is increasingly appreciated in clinical practice. A central role for Western diets as a rheostat for gut inflammation was demonstrated for IBD in the last years, and particular dietary patterns and food constituents have been linked to the development and cou...

J. Schwärzler, H. Tilg, T. Adolph · 0 citations

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