Author

T. Bosse

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Open access Oct 2026

Predicting HPV/p16 Status and Molecular Subtypes from Histopathology Slides using Deep Learning in Vulvar Squamous Cell Carcinoma

Vulvar squamous cell carcinoma (VSCC) comprises three prognostically distinct molecular subtypes: human papillomavirus (HPV)-associated, HPV-independent/p53-wildtype, and HPV-independent/p53-abnormal. Classification requires p16/p53 immunohistochemistry, which consumes tissue and is often incomplete in retrospective co...

N. J. van den Berg, W. L. Van der Kolk, K. Landsbergen et al. · medRxiv · 0 citations

Review Oct 2026

Updates on the Molecular Classification of Endometrial Carcinoma.

The risk of recurrence and metastasis in patients with endometrial carcinoma varies widely, making evaluation of risk in individual patients critically important for planning effective adjuvant treatment. Tumor histotype and grade have been used, along with stage and lymphovascular space invasion (LVSI), but suboptimal...

K. K. van de Vijver, C. Gilks, T. Bosse · Advances in Anatomic Patholo... · 0 citations