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Open access Sep 2026

The GrimAge clock corresponds to brain ageing and social determinants of health in people with HIV.

BACKGROUND DNA methylation (DNAm)-based epigenetic clocks can measure biological ageing. However, newer epigenetic clocks sensitive to morbidity, mortality, and longitudinal change have not been compared to brain health biomarkers in virally suppressed people with HIV (PWH) and without HIV (PWoH). METHODS Participant...

Kalen J. Petersen, Seungjae Kim, Pete Canfield et al. · 0 citations
Open access Jul 2026

Inflammatory, Cardiac, and Lipid-Related Biomarkers in Relation to Residual MACE Risk in the REPRIEVE Trial

Background Residual major adverse cardiovascular event (MACE) risk persists despite successful prevention of cardiovascular disease (CVD) with statin therapy among people with HIV (PWH). Identifying key biomarkers related to residual cardiovascular risk is critical for PWH. Objectives The objective of the current analy...

S. Grinspoon, C. deFilippi, T. Umbleja et al. · 1 citation

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