Factors Influencing the Selection of α-Amino Acids over β-Amino Acids in Nature: Studies Involving Protein-l-isoaspartyl Methyltransferase Substrates and Related Peptides.
To understand the differences resulting from the presence of an α- or β-amino acid in a peptide, we used two sets of amino acids corresponding to Asp/isoAsp and Ala/isoAla in two types of host peptides: one containing Gly (with no side chains) and the other containing Ala (representing amino acids with side chains), an...