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T. D. C. Hirata

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Open access Sep 2026

ADRB3, LEPR, FTO and PPARG variants contribute to obesity-related metabolic syndrome in Brazilian adults: a polygenic risk score approach.

OBJECTIVE Polymorphisms in genes involved in obesity-related metabolic pathways are associated with metabolic syndrome (MetS). We hypothesized that variants in FTO, LEP, LEPR, ADRB3, ADIPOQ, TCF7L2, ENPP1, APOA5, PPARG, and CYP11B2 are associated with MetS and obesity-related traits. METHODS A group of 420 subjects (...

Tamiris Invencioni Moraes Stefani, T. D. C. Hirata, Álvaro Cerda et al. · 0 citations

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