Open access
Aug 2026
Secreted nuclease effector neutralization by active site mimicry in Bacillota
ABSTRACT Polymorphic toxins mediate interbacterial antagonism among competitors in the gut microbiome. Nuclease effectors, distantly related to the type VI-secreted Bacteroidales Tde, are enriched in human gut Bacillota. Tde mediates antagonism among Bacillota, and expression of the cognate immunity, Tdi, in recipients...
Romina Abbasian, Bishal Parajuli, Liping Yu et al.
· mBio · 0 citations