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Open access Sep 2026

Melatonin Differentially Modulates Temozolomide Responses in Glioblastoma and Endothelial Cells: Associations with Global DNA Methylation and Cortistatin Levels

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults and remains highly resistant to current therapeutic strategies. Temozolomide (TMZ) is a standard chemotherapeutic agent used in GBM treatment; however, intrinsic and acquired resistance limits its efficacy. This study investigated treatment-associa...

G. Gundogan, A. Yurttaş, Y. Oltulu et al. · 0 citations
Open access Jul 2026

Age-Adjusted Associations Between Routine Systemic Inflammatory Markers and Anti-Müllerian Hormone in Reproductive-Age Women: A Retrospective Cross-Sectional Study

Background: Anti-Müllerian hormone (AMH) is widely used as a marker of ovarian reserve and is strongly influenced by chronological age. Although inflammation has been implicated in ovarian aging and follicular dysfunction, whether routinely measured peripheral inflammatory markers provide additional information regardi...

Mete Hakan Karalök, Bağnu Dündar, Ayhan Parmaksiz et al. · 0 citations

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