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T. Exarchos

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Open access Oct 2026

Enrich.AI: An Agentic AI Platform for Interactive Gene Set Enrichment Analysis and Biological Interpretation

Motivation Enrichment analysis is widely used to extract biological meanings from gene lists. However, the large number of available tools and reference libraries often make the interpretation of results challenging. Inexperienced users lack clear guidance on which datasets and terms are most relevant to their data, wh...

Dimitrios E. Koumadorakis, T. Exarchos, Panayiotis M. Vlamos et al. · 0 citations
Open access Sep 2026

APOE4 differentially alters lipid composition in extracellular vesicles from hiPSC-derived neurons of Alzheimer’s disease patients

Background The Apolipoprotein E4 (APOE4) is the most significant genetic risk factor for late-onset Alzheimer’s disease (AD), but the cellular mechanisms by which it increases vulnerability remain poorly understood. Lipids play a crucial role in membrane organization, vesicle trafficking, and inflammatory signaling in...

Marios G. Krokidis, Ram Sagar, Maja Mustapić et al. · 0 citations

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