Author

T. Galica

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Open access Sep 2026

Structural and Stereochemical Elucidation of Cyanochelin C, a Siderophore Associated with Novel Class of Cyanobacterial Acyl Hydrolases

A novel cyanobacterial siderophore, cyanochelin C, that employs two β-hydroxyaspartate residues for iron chelation and its deacylation by CcsQ expands the known structural diversity of cyanobacterial siderophores and improves the understanding of important enzymatic reactions.

Viviana Di Matteo, L. Štenclová, B. P. Falcao et al. · bioRxiv · 0 citations

Open access Jul 2026

Utilization of cyanobacterial siderophore cyanochelin B by phylogenetically distant heterotrophs suggest its role in mediating microbial interactions

The results indicate that CychB supports a specific subset of co-habiting heterotrophic bacteria during iron starvation, further emphasizing the role of cyanobacteria as key drivers of nutrient flows within globally important microbial soil crust ecosystems, supporting microbial life in nutrient-limited environments.

B. P. Falcao, Martinez Yerena Jose Alberto, T. Galica et al. · bioRxiv · 0 citations

Open access Jul 2026

Cyanochelin uptake reveals an exclusively cyanobacterial class of AMIN-domain TonB-dependent transporters

This study functionally characterise the import system of cyanochelin B, a photolytic β-hydroxy aspartate siderophore produced by several filamentous cyanobacteria, and reports the first functional heterologous expression of a cyanobacterial TonB-dependent transporter and establishes Synechocystis as a promising platfo...

Jan Mašek, B. P. Falcao, Lucie Kajan Grodecká et al. · bioRxiv · 0 citations