Author

T. Gnanasekaran

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Sep 2026

Bioactive Compounds of Oroxylum indicum L. Kurz Stem Bark and Their Anti-Inflammatory Significance.

The anti-inflammatory potential of Oroxylum indicum (OI), a traditional medicinal plant, was evaluated through in vitro, ex vivo, and molecular docking studies. The stem bark extract exhibited a significant, dose-dependent inhibition of protein denaturation in both egg albumin and bovine serum albumin assays at concent...

Sushma Swaroopa, T. Gnanasekaran, Nanditha Bhat et al. · Prostaglandins & other lipid... · 0 citations

Open access Sep 2026

UPLC-MS metabolite profiling and antioxidant efficacy of Neopestalotiopsisclavispora isolated from Oroxylum indicum (L.) Kurz Stem Bark

Endophytic fungi represent a valuable source of bioactive compounds with diverse pharmacological properties. In this study, we explored the antioxidant potential of secondary metabolites produced by Neopestalotiopsis clavispora (N.clavispora), an endophytic fungus isolated from Oroxylum indicum Kurz stem bark. N.clavis...

Sushma Swaroopa, Amshumala Bhoothakallu Lolajaksha, T. Gnanasekaran et al. · PLoS ONE · 0 citations

Aug 2026

Targeting methyl-accepting chemotaxis transmembrane sensory protein inhibits Helicobacter pylori autoinducer-2 quorum sensing system

Findings suggest that Withaferin A and Obacunone could serve as promising therapeutic agents against H. pylori infections by disrupting quorum sensing and biofilm formation, thus addressing the challenge of antibiotic resistance in this pathogen.

Thejaswi Bhat, Manish Kumar, T. Gnanasekaran et al. · Biologia · 0 citations