T. Hanff

Left Ventricular Functional Improvement is Associated With Lower Morbidity and Mortality During Long-Term Mechanical Circulatory Support: An STS Intermacs Analysis.

BACKGROUND A subset of patients with advanced heart failure (HF) supported with durable left ventricular assist devices (LVADs) demonstrate significant improvement in left ventricular ejection fraction (LVEF), but the impact of such functional improvement on clinical outcomes is unclear. METHODS We analyzed adults in...

Artificial Intelligence-Enabled Detection and Management of Physiological Instability in Heart Failure: Results of the Randomized LINK-HF2 Trial.

BACKGROUND Artificial intelligence (AI)-enabled wearable monitoring can detect individualized physiological deviations preceding heart failure (HF) decompensation, but whether these signals can be translated into improved outcomes remains uncertain. OBJECTIVES This study aims to evaluate the feasibility of integratin...

Why guideline-directed medical therapy depends on more than guidelines: microeconomics of medication use in heart failure

Ventricular Strain Predicts the Risk of Right Heart Failure After Durable Left Ventricular Assist Device Implantation

Background Right heart failure (RHF) is prevalent after left ventricular assist device (LVAD) implantation and associated with poor short- and long-term outcomes. The interaction of the right ventricle (RV) with its afterload before LVAD implantation may impact the incidence of RHF. Objectives The aim of the study was...