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Open access Nov 2026

Plasma metabolomic profiling to predict durable response and survival with afatinib in EGFR-mutated non-small cell lung cancer: A prospective, multicenter, observational biomarker study

While EGFR tyrosine kinase inhibitors (TKIs) like afatinib are standard treatments for EGFR-mutated non-small cell lung cancer (NSCLC), predicting which patients will achieve durable responses remains challenging. Given the emergence of more toxic and costly combination therapies, identifying candidates who can ach...

T. Honda, K. Morikawa, Saori Takata et al. · 0 citations

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