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Author

T. Ishikawa

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Oct 2026

Prognostic Significance of PET− SUVmax in Patients Undergoing Resection of Hepatocellular Carcinoma >3 cm: A Retrospective Analysis

Background/Aim: Hepatocellular carcinoma (HCC) >3 cm often recurs after resection, indicating a need for better risk stratification. The 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) maximum standardized uptake value (SUVmax) reflects tumor aggressiveness. We evaluated the prognostic significance of pre...

T. Ishikawa, S. Itoh, Y. Kitamura et al. · 0 citations
Open access Aug 2026

Spatiotemporal dynamics of the tumor microenvironment in hepatocellular carcinoma during combination immunotherapy

The exploratory findings suggest that ATZ/BEV may remodel the HCC microenvironment toward a state characterized by concurrent CD8+ T-cell activation and inhibitory signaling through the TIGIT–PVR/NECTIN2 axis, particularly at the tumor margin.

Hitoshi Iwasaki, S. Itoh, K. Toshida et al. · 0 citations

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