Author

T. K. Maiti

3 papers indexed here

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Open access Sep 2026

Metabolic modeling with reverse mapping links host perturbations to Mycobacterium tuberculosis

Summary Understanding host-pathogen interactions during Mycobacterium tuberculosis (Mtb) infection has largely relied on identifying bacterial genes essential for intracellular survival. However, conventional reverse genetics approaches often overlook host pathways that regulate Mtb growth. Here, we developed a backtra...

Jayendrajyoti Kundu, Vishawjeet Barik, Abhijit Paul et al. · iScience · 0 citations

Open access Aug 2026

Supplementation of αKG along with TGFβ/HIF1α antagonist rescues lung fibrosis in mice with severe SARS-CoV-2 infection

The study demonstrated the upregulation signalling molecules like P-AKT, TGFβ and HIF1α and their association with pulmonary fibrosis in mice after severe SARS-CoV-2 infection and described the HIF1α axis as the therapeutic target in rescuing post-acute sequelae such as ARDS and fibrosis in mice with severe SARS-CoV-2...

Garima Joshi, G. Parveen, Simrandeep Kaur et al. · Journal of Translational Med... · 0 citations

Open access Sep 2026

Host- and pathogen-regulated exocytosis facilitates dynamic distribution of endolysosomal content during infection by the vacuolar pathogen Coxiella burnetii

ABSTRACT Coxiella burnetii is an obligate intracellular bacterial pathogen that causes the zoonotic disease Q fever. Coxiella extensively subverts host vesicle traffic and replicates within lysosome-derived, spacious vacuoles by secreting a suite of effectors through the type IVB secretion system (T4BSS). This study in...

Hrithik Kumar, Amrita Bhattacharya, Sayanthana Benny et al. · Infection and Immunity · 0 citations