Open access
Oct 2026
Functional characterization of a 3-O-sulfate tolerant heparin lyase from Bacteroides eggerthii.
Heparin is a sulfated glycosaminoglycan, and the most used pharmaceutical anticoagulant worldwide. Heparin is isolated primarily from porcine sources, and possesses a complex variable structure, wherein anticoagulant activity is principally derived from the pentasaccharide GlcNS6S-GlcA-GlcNS3S6S-IdoA2S-GlcNS6S (AGA*IA)...
T. Kandola, C. J. Mycroft-West, Marcelo A. Lima et al.
· Glycobiology · 0 citations