Author

T. Kazda

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Review Open access Aug 2026

The specificity trap in routine tumor biomarker interpretation: Advancing the 3PM-based clinical decision framework to benefits of patients

Routine tumor biomarkers remain among the most accessible tools in oncology. Yet, their clinical value is frequently weakened by a persistent specificity trap: abnormal results are often treated as cancer-specific signals, whereas normal results are sometimes used to reassure against malignancy. This critical narrative...

P. Kubatka, Ludmila Filkova, I. Slaninová et al. · The EPMA Journal · 0 citations

Open access Aug 2026

Radiotherapy Modality and Primary Tumor Type as Determinants of Outcomes in Brain Metastases: A Retrospective Study of 734 Patients

Overall survival varies significantly across primary sites with most favorable outcomes in breast cancer patients irradiated with SRS/FSRT, with most favorable outcomes in breast cancer patients irradiated with SRS/FSRT.

L. Hnidakova, Andrea Pagacova, Sarka Kristkova et al. · Medicina · 0 citations

Review Open access Aug 2026

Ovarian cancer tumor immune microenvironment and its clinical trial implications

This narrative educational review aims to provide a comprehensive overview of recent advances in the understanding of ovarian cancer pathogenesis, the molecular mechanisms driving tumor progression, and the multifaceted role of the immune system in disease development and therapeutic response.

B. Vavrušáková, R. Bartošová, M. Hendrych et al. · Discover Oncology · 0 citations