Open access
Sep 2026
Enhancing the Scalable Manufacturing of Human Mesenchymal Stromal Cells in Dynamic Culture Using Bioactive Heparin/Collagen Layer‐by‐Layer Coated Microcarriers
Expansion of human mesenchymal stromal cells (hMSCs) remains a bottleneck during manufacturing, where high cell yields must be achieved without compromising quality. Microcarriers provide elevated surface areas but often rely on synthetic materials. Here we use heparin/collagen Layer‐by‐Layer (LbL) coatings on microcar...
Justin Putman, Varsha Karunakaran, Roaa Hadi et al.
· Biotechnology Journal · 0 citations