Discovery of a buried charge-network GFP-fold family spanning prokaryotes and eukaryotes
Findings expand the known sequence and chemical space of the GFP barrel, although the biochemical function of the network remains unknown, and identify the same two-cation/two-anion/tyrosine network in 238 members of DUF2490, an unrelated outer-membrane beta-barrel family consistent with convergent evolution of the bur...