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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

T. Li

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Sep 2026

ADSC‐Exosomes Preserve Mitochondrial Function and Ameliorate Uranyl Acetate‐Induced Nephrotoxicity Through Inhibition of ATF4 and Activation of PGC‐1α/NRF/Tfam Pathway

Uranyl acetate (UA)‐induced renal injury disrupts mitochondrial ultrastructure and homeostasis through oxidative stress‐mediated pathways, with activating transcription factor 4 (ATF4) identified as a critical molecular switch. This study demonstrates ATF4 directly suppresses peroxisome proliferator‐activated receptor...

Lei Li, T. Li, Bei Fang et al. · 0 citations

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