Author

T. Mollnes

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Open access Oct 2026

Integrative multi-omics reveals CUL4B as a modulator of macrophage pyroptosis and innate defense against Staphylococcus aureus.

Staphylococcus aureus (SA) causes a broad range of invasive human diseases, increasingly complicated by antibiotic resistance. Macrophages (MΦ) play a central role in innate immunity, yet key aspects of their interaction with SA remain incompletely understood because of the pathogen's diverse immune evasion strategies....

Fatemeh Askarian, Daniel Sun, Jasmine Tat et al. · Science Advances · 0 citations

Open access Oct 2026

Supernatants from stored platelet concentrates modulate the inflammatory response in platelet-depleted blood ex vivo

Platelets contain a wide range of bioactive mediators, many of which accumulate during storage of platelet concentrates and have immunomodulatory properties. Our objective was to investigate how mediators derived from stored platelet concentrates modulate the acute inflammatory response using an ex vivo model....

Linnea I. Andersson, D. Sjöström, N. Tynngård et al. · Frontiers in Immunology · 0 citations