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Open access Jul 2026

Revealing NMOSD Molecular Mechanisms in an AQP4-Induced Animal Model 2261163

The findings show that NMOSD is driven by antigen-specific T and B cell responses, amplified by IFN-I and innate CNS dysregulation, and PLGA(AQP4) therapy re-establishes tolerance and offers a translational strategy for CNS autoimmunity.

G. Arellano, Mac Zelazny, T. Neef et al. · 0 citations

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