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Open access Sep 2026

Immune remodeling and myeloid signature in the bone marrow niche of MYCN-driven neuroblastoma

High-risk MYCN-amplified neuroblastoma is associated with a dire prognosis and often metastasizes to the bone marrow. However, systemic immune remodeling and its effect on the bone marrow niche remain unclear. Harnessing single-cell RNA sequencing, we compare the bone marrow immune cell landscape of wild-type (WT) mice...

Bethel Tesfai Embaie, A. Alchahin, Lilly Velentza et al. · 0 citations

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