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Open access Sep 2026

Non-parametric differential methylation analysis characterizes histotype-specific promoter regions in epithelial ovarian cancer

ABSTRACT Epithelial ovarian cancer (EOC) is a heterogenous disease with frequent late-stage diagnosis and high mortality rates, for which no reliable screening tests exist. In recent years, epigenetic biomarkers in the form of DNA methylation in CpG-rich regions have gained increased attention in the scientific communi...

Hugo Swenson, Ella Ittner, Lucas Werner et al. · 0 citations
Open access Aug 2026

Spheroid cultures reveal cancer stem cell enrichment and distinct chemotherapeutic response in triple-negative breast cancer

Three-dimensional cancer spheroids mimic key morphological and biological features of solid tumors, providing a valuable model for evaluating drug responses and novel insight into the mechanisms underlying 3D growth and chemoresistance that may help inform future therapeutic strategies.

Sithumini Sarathchandra, Chiara Fittipaldi, N. A. Alamukii et al. · 0 citations

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