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T. Periyasamy

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Open access Aug 2026

Molecular dynamics-guided engineering of penicillin G acylase for enhanced β-lactam biosynthesis

Penicillins and cephalosporins are crucial in treating bacterial infections, but conventional chemical synthesis routes for their production are costly and environmentally burdensome. Enzymatic alternatives, such as penicillin G acylase (PGA), offer a greener path; however, naturally occurring forms of this enzyme ofte...

Sam Peniel Richard, Prajval Ramesh, Asiya Azarudeen et al. · 0 citations

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