FREEZE-DRIED BINARY AND TERNARY SOLID DISPERSIONS OF CANNABIDIOL: FORMULATION, CHARACTERIZATION, AND SOLUBILITY ENHANCEMENT
Objective: Cannabidiol (CBD) is a non-psychoactive phytocannabinoid with broad therapeutic potential. However, it’s extremely poor aqueous solubility limits pharmaceutical development. This study aimed to enhance CBD solubility using binary and ternary amorphous solid dispersions (SDs) prepared by freeze-drying. Method...