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Author

Ting Quan

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2 papers indexed here

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Open access Oct 2026

Efficacy and safety of SYH2053 in patients with primary hypercholesterolemia or mixed dyslipidemia: a phase II, multicenter, randomized, double-blind, placebo- and active-controlled trial

SYH2053 is a novel small interfering RNA (siRNA) drug targeting proprotein convertase subtilisin/kexin type 9 (PCSK9), with optimized full-sequence chemical modification and N-acetylgalactosamine conjugation, which demonstrated a stable and sustained lipid-lowering efficacy in the phase I study in heathy particip...

F. Wang, Shu-Yi Zeng, S. Zhang et al. · 0 citations
Open access Oct 2026

Efficacy and Safety of Chemically Synthesized Semaglutide Injection (HD1916) for the Treatment of Obesity: A Multicenter, Randomized, Phase III Trial.

AIMS To evaluate whether HD1916, a chemically synthesised semaglutide, is therapeutically equivalent to the reference product semaglutide (Wegovy) in body weight reduction among Chinese adults with obesity without diabetes. MATERIALS AND METHODS This multicenter, randomised, open-label, active-controlled Phase III tr...

Lei-Li Gao, Yu-Jin Ma, Qiu-Mei Zhang et al. · 0 citations

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