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Author

T. Rengers

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Open access Aug 2026

Therapeutic targeting of cancer-associated fibroblasts with oncolytic virus in preclinical models of intrahepatic cholangiocarcinoma

Intrahepatic cholangiocarcinoma (iCCA) is an aggressive malignancy with limited effective therapies. Treatment resistance is partly due to activated cancer-associated fibroblasts (CAFs), which induce pro-tumor signaling and formation of a highly fibrotic tumor microenvironment. CAFs exist on a functional spectrum of su...

A. Abeynayake, T. Rengers, D. Carlson et al. · 0 citations

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