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T. Schreiner

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Open access Oct 2026

Precision Medicine in Epilepsy: Diagnostic Yield by Next-Generation Sequencing and Genotype–Phenotype Findings in a Romanian Cohort

pilepsy ranks among the most prevalent neurological disorders globally, with a substantial proportion of cases, particularly in pediatric populations, attributed to genetic etiologies. This study provides the first molecular characterization of suspected genetic epilepsy in a pediatric cohort from the Moldova region of...

L. Butnariu, Ecaterina Grigore, T. Schreiner et al. · 0 citations
Review Open access Sep 2026

GLP-1, GIP, and Glucagon Receptor Agonism at the Obesity–Neurodegeneration Interface: A Narrative Review

Glucagon-like peptide-1 receptor agonism has attracted interest in neurodegeneration because of its effects on metabolic and inflammatory pathways implicated in neuronal dysfunction. This narrative review examines the molecular rationale and neurological evidence for selective glucagon-like peptide-1 receptor agonists,...

E. Popa, A. Popa, V. Poroch et al. · 0 citations
Review Open access Aug 2026

Selective Neuronal Vulnerability to Alpha-Synuclein Pathology in Parkinson’s Disease: A Critical Review of Mechanistic Rationale and Biomarker Stratification

The Parkinson’s Vulnerability Index (PVI) is proposed, a hypothesis-generating multidimensional model combining genetic, enzymatic, alpha-synuclein seeding, cognitive, olfactory, and neuroimaging biomarkers to facilitate biological stratification and improve the design of mechanism-targeted clinical trials.

Livia Livinț-Popa, Andreea Nicolaie, A. Maștaleru et al. · 0 citations

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