The renin-angiotensin system (RAS), traditionally recognized for cardiovascular and renal regulation, has emerged as a critical mechanistic player in neuropsychiatric pathophysiology. The brain possesses its own independent RAS with components located throughout limbic regions, cortical areas, and monoaminergic circuit...
Akhil Sharma, Tanya Goel, Ashi Mannan et al.· Hormones and Behavior· 0 citations
The human genome encodes a wide variety of protein kinases that regulate multiple cellular functions. These enzymes play a crucial role in amplifying and propagating intracellular signals during signal transduction. Dysregulation of protein kinase signaling is associated with vascular diseases, inflammatory disorders,...
Rajwinder Kaur, D. K. Lang, Ankita Sood et al.· RSC Advances· 0 citations
This model highlights how gut dysbiosis alters systemic metabolite profiles, how these metabolites regulate renal autophagic activity, and how impaired autophagy further promotes metabolic and inflammatory reprogramming in CKD progression.
Khemender Lidoo, Rupinder Kaur, Ravinder Singh et al.· International Immunopharmaco...· 0 citations
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