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Sep 2026

Adolescent Ethanol Exposure Reduces Central Amygdala GABA Transmission But Preserves Noradrenergic Signaling In Adulthood.

Early initiation of alcohol use is a risk factor for developing alcohol use disorder (AUD) later in life, yet the long-term neuronal consequences of adolescent drinking remain poorly understood. The central amygdala (CeA) drives the negative emotional states that promote excessive drinking, and its overactivation is a...

Paige Marsland, Peter T. Penta, T. T. Towner et al. · 0 citations
Review Open access Aug 2026

Neuromodulators of orbitofrontal cortex function: A review of endocannabinoid, neurotrophin, and cell adhesion systems

The impacts of endocannabinoids, the neurotrophin Brain-derived Neurotrophic Factor, and cell adhesion systems in both medial and lateral compartments of the OFC are summarized to highlight other neuromodulatory factors that have received less attention but are also potent regulators of OFC-dependent decision making.

Sophie T. Yount, T. T. Towner, S. Gourley · 0 citations

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