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Author

T. Trokhymchuk

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Oct 2026

METHODS FOR DETERMINING THE MECHANISM OF TARGETED PROTEIN DEGRADATION

Summary. Targeted protein degradation (TPD) is a modern strategy for developing new therapeutic agents that requires not only detection of decreased target abundance but also stepwise validation of the compound’s mechanism of action. In this approach, the disappearance of the target protein is necessary but insufficien...

O. Vasylchenko, T. Trokhymchuk, M. Arkhypova et al. · 0 citations

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