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Open access Sep 2026

BigHeart: Mapping connectivity in the adult human heart at the micron scale

The human heart depends on coordinated muscular, electrical, vascular, lymphatic, and neural systems, but their three-dimensional relationships remain unresolved at microscopic resolution across an intact adult organ. Using hierarchical phase-contrast tomography, we generated a continuous three-dimensional structural r...

J. Brunet, A. C. Cook, A. Szmul et al. · 0 citations
Open access Sep 2026

Multi-modal analysis of vascular remodelling in human obliterative bronchiolitis after lung transplantation.

Chronic lung allograft dysfunction (CLAD) is the leading cause of late morbidity and mortality after lung transplantation. Bronchiolitis obliterans syndrome (BOS), a major CLAD phenotype, is characterized by obliterative bronchiolitis (OB). While microvascular perturbations are described in BOS, their cellular and mole...

Axelle Coppens, Rahel Bodenmann, Janik Riese et al. · 0 citations

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