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T. Welton

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Open access Sep 2026

Analysis of east Asian Parkinson's disease Genomes Identifies Novel Susceptibility Loci and Functional Regulatory Variation

Background: Parkinson disease (PD) is a genetically complex neurodegenerative disorder, but most genetic discoveries have been derived from populations of European ancestry, limiting the understanding of ancestry-specific genetic risk. Methods: This GWAS included 5,825 East Asian participants (3,043 patients with PD an...

Q. Sun, E. Ng, T. S. Toh et al. · 0 citations
Open access Jul 2026

Choroid plexus enlargement is negatively associated with cognitive performance in a DTI-ALPS–dependent manner

CP enlargement is associated with glymphatic diffusion, and its relationship with cognitive performance varies across DTI-ALPS index values, suggesting that interactions between CSF regulatory systems may correlate with cognitive performance in a state-dependent manner.

N. Tan, T. Welton, Yi Jayne Tan et al. · 0 citations

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