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Tadashi Nomura

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Open access Jul 2026

Disruption of Histone H4C genes impairs skeletal development and cortical neurogenesis, modeling rare neurodevelopmental syndromes

It is demonstrated that histone H4C genes play crucial roles in skeletal development and cortical neurogenesis and suggest that histone H4 plays a critical role in regulating the balance between proliferation and differentiation during mammalian embryonic development, thereby explaining the broad spectrum of patient ph...

Haruna Nagasawa, Kaneyasu Nishimura, Sayaka Tojima et al. · 0 citations

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