Aug 2026
Discovery of synthetic TBK1 activator inducing type I interferon mediated antiviral and antitumor immunity.
Type I interferons (IFNs) are central regulators of innate immunity, coordinating antiviral defense and tumor immune surveillance. However, therapeutic strategies that selectively engage IFN signaling while maintaining controlled outputs remain limited. Here, we identify a synthetic small molecule that induces robust t...
Kwiwan Jeong, Subin Hong, Pin Liu et al.
· Molecular Therapy · 0 citations