Author

Tai Sun

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Open access Jul 2026

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

An association between reduced P53 function and increased expression of the epigenetic regulator TET1 in GBM models is identified, suggesting that TET1 may serve as a potential mediator of therapy resistance and a promising therapeutic target in TP53mut GBM.

Zhuonan Pu, Jinqiu Liu, Yuxuan Deng et al. · Advancement of science · 0 citations

Aug 2026

Combining Type I&II Photosensitizer With Hypoxia-Activated Prodrug Enables Oxygen-Unrestricted Synergistic Photocatalytic Therapy.

This work provides an oxygen-unrestricted synergistic strategy to compensate for the limitations of standalone Type II PSs or HAPs monotherapy, offering valuable insights for clinical cancer treatment.

Haoran Hou, Hanhan Lu, Yingnan Wu et al. · Small · 0 citations