Taiichi Sakamoto

Expanding the Frontiers of Structural Analysis in Short RNAs by Ultra-High Field 1.3 GHz NMR

Residual dipolar couplings (RDCs) obtained via magnetic field-induced alignment offer a powerful, media-free approach for the structural analysis of biomolecules. However, their detection in short, fast-tumbling nucleic acids remains elusive at conventional magnetic fields due to insufficient alignment and sensitivity....