Estrogen-dependent regulation of lipolysis-stimulated lipoprotein receptor via G-protein-coupled estrogen receptor 1 in breast cancer malignancy.
The lipolysis-stimulated lipoprotein receptor (LSR) is a tight junction protein implicated in tumor progression, yet its regulatory mechanisms in breast cancer (BC) remain unclear. We found that high LSR expression correlates with poor overall survival in BC patients. RNA interference-mediated LSR knockdown significant...