T follicular helper cell lymphomas (TFHL) harbor activating T cell receptor (TCR) signaling mutations and epigenetic alterations, such as TET2 mutations. Here, we conduct a multi-center, single-arm, phase 2 trial of the tyrosine kinase inhibitor dasatinib in patients with relapsed/refractory TFHLs (jRCT2031190079). The...
S. Suma, M. Sakata-Yanagimoto, Y. Suehara et al.· Nature Communications· 0 citations
Donor-specific HLA antibodies (DSA) are associated with graft failure after HLA-mismatched allogeneic hematopoietic stem cell transplantation (HSCT). The most widely used method for identifying anti-HLA antibodies is the single-antigen bead (SAB) assay. Although this method has high sensitivity, it also detects natural...
Takayo Sakurazawa, S. Shiratori, Makoto Ito et al.· Transplant Immunology· 0 citations
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