Open access
Aug 2026
PfAMA1-expressing chimeric rodent malaria parasites provide an in vivo platform for evaluating multistage interventions against malaria
Apical membrane antigen 1 (AMA1) is expressed in the merozoite and sporozoite infectious stages of the malaria parasite, and upon secretion plays essential roles during host cell invasion. AMA1 is a leading candidate for vaccine development, although specific antibodies frequently fail to inhibit the growth of field-is...
Quratul-ain Issahaque, Naoaki Shinzawa, Yuto Kegawa et al.
· bioRxiv · 0 citations