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Author

Takuji Kawamura

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Review Open access Sep 2026

Integrated Multi-Omics Network by Physical Exercise Across Aging: Molecular Adaptation Beyond Single Signaling Pathways.

A multi-omic framework in which exercise acts as a coordinated biological stimulus capable of remodeling age-associated molecular dysfunction across genomic, epigenomic, transcriptomic, proteomic, and metabolomic layers is proposed, supporting the concept that healthy aging is dynamically regulated and that age-associa...

Guilherme da Silva Rodrigues, I. V. de Sousa, Takuji Kawamura et al. · 0 citations
Open access Sep 2026

Methylome-transcriptome integration reveals molecular signatures of intrinsic aerobic capacity in aged skeletal muscle.

Intrinsic high aerobic capacity in aged skeletal muscle is associated with hypermethylation-enriched methylome remodeling, feature-dependent functional enrichment, distinct transcriptional signatures, and oxidative-metabolic protein differences.

Lei Zhou, S. Mozaffaritabar, F. Torma et al. · 0 citations

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